Extrapyramidal features in advanced Down's syndrome: clinical evaluation and family history.

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Extrapyramidal features in advanced Down's syndrome: clinical evaluation and family history.

Extrapyramidal, frontal release, and other neurological signs were studied in 54 demented and non-demented patients with Down's syndrome (DS). Fourteen patients were demented and five showed extrapyramidal signs, mainly of the rigid-hypokinetic spectrum and similar to Parkinsonian features in advanced Alzheimer's disease (AD). None of the non-demented patients had Parkinsonian signs. The mean a...

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ژورنال

عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry

سال: 1991

ISSN: 0022-3050

DOI: 10.1136/jnnp.54.1.34